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If a patient reaches 2.4 mg and is still not achieving clinically meaningful weight loss (defined as at least 5 percent of body weight), the medication may not be the right fit

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The tirzepatide dose had been escalated from 7.5 mg to 10 mg in February 2023 and further increased to 12.5 mg on March 27, 2023, four days prior to the onset of acute abdominal pain