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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

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Currently Shipping Analytical Results Sterility Testing Independent sterility testing was performed by Eurofins Biopharma Product Testing under EP 2.6.1, USP , and JP 4.06 methods

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