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Of these, 2-fold differences in gene expression were identified for 336 gene transcriptsthe most significantly differentially expressed genes are summarised in Supplementary Table 1 (Supplementary Information), and changes in gene expression predicted by BeadChip Array analysis confirmed by qRTPCR analysis for selected up- and downregulated genes (Figure 4)
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In animal TLE models, HMGB1 acts through TLR-4 to increase production of cytokines such as IL-1, TNF, and IL-6 (Maroso et al., 2010)
Rehman K, Ali MB, Akash MSH
2.6 Meta-analysis Meta-analysis was performed using the R statistical program, R version 4.4.2 (The R Foundation for Statistical Computing, Wirtschaftsuniversitt Wien, Vienna, Austria) (Sterne et al., 2016
