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The cause and effect of errors in the control mechanisms of GCL are slowly being unravelled by researchers and is the subject of several excellent reviews [2-6]
The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers
Goal-Specific Dosing Considerations The optimal MOTS-c dose is not one-size-fits-all: it shifts depending on whether the clinical goal is metabolic correction, athletic performance enhancement, or anti-aging and longevity support
These effects are attributed to the action of enzymes, such as the activation of glutathione reductase, the improvement of insulin resistance, and the inhibition of protein glycosylation
