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one Phase II skin trial Evidence gap / no head-to-head or combination RCT exists as of 2025 Typical sermorelin dose / 200-500 mcg subcutaneous injection at bedtime Typical GHK-Cu dose / 1-2 mg subcutaneous or topical, 5 days per week Regulatory status / sermorelin: FDA-approved (NDA 19-559, withdrawn 2008 for commercial reasons)
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Wound Repair and Regeneration .Read source (2000)
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Endocrinology Research: This combination is studied for its effects on the incretin-amylin hormonal axis and pancreatic beta-cell function
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