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A considerable number of evidences provided by Sikiric et al
Best practice is to get written documentation rather than verbal
Most long-term protocols settle at 12 mg per day because the doseresponse curve plateaus
Review these records regularly to identify storage problems
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The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers
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