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The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint
A nagging tendon injury had sidelined him for months, and physical therapy was progressing slower than hed hoped
There appear to be two ways that it does so
By inhibiting NNMT activity, 5-Amino-1MQ modulates enzymatic processes associated with nicotinamide metabolism, methylation network regulation, and intracellular cofactor-associated signaling systems
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