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New Drugs , 29 , 25802585 (China, 2020)

Journal of Diabetes and Metabolic Disorders , vol

For diabetes treatment doses, weight loss typically ranges from 2-5% of baseline body weight

These findings are powerfully convergent with in vivo observations in animal models, which confirm that these cellular insults translate into functional consequences: neuroinflammation, synaptic dysfunction, and ultimately, behavioral deficits such as anxiety, cognitive impairment, and social withdrawal

However, there are no compensatory behaviors to control weight, such as vomiting, fasting, exercising or laxative misuse

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