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Lee et al., 2011
Often combined with other actives like vitamin C, niacinamide, and hyaluronic acid, if you want to incorporate it in your skincare routine, speak to your doctor, who can advise you based on your personal and medical history
Antitumor properties of triptolide: phenotype regulation of macrophage differentiation
Steinhart AH et al
However, up to 10% undergoes bioactivation to N -acetyl p -benzoquinone imine (NAPQI), a highly reactive electrophile, which is known to covalently bind to nucleophilic centers, including cysteine thiols in liver proteins (see Figure 1) (Jollow et al., 2015)
Sp could efficiently restore redox balance in cells depleted for antioxidant properties or with dysfunctional mitochondria, mainly by enhancing the reducing potential of the cell through efficient recycling of GSH
