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Finally, participants were filtered on relatedness such that no two people shared more than 700 cM identity by descent 37 , which corresponds approximately to the minimal expected sharing between first cousins in an outbred population, resulting in a final GWAS sample size of 15,237

Preconception folic acid supplementation (400-800 mcg daily) is recommended for women who might become pregnant

May cause weight loss Neither medication is FDA-approved as a weight loss drug

Patent number 4,602,039 *These statements have not been evaluated by the Food & Drug Administration

Titration addresses this