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Examples include: Medical contraindications to GLP-1 therapy Lack of clinical supervision No structured plan for muscle preservation Hormonal status not yet evaluated Reducing the dose does not remove contraindications or eliminate underlying medical risks

The titration schedule can be as follows (for example): Month 1: Women: 1.5 mg once weekly Men: 1.8 mg once weekly (Note: The standard starting dose is 2.5 mg weekly

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Kuria A, Tian H, Li M, Wang Y, Aaseth JO, Zang J, et al

Although the screening program has met with success, the lack of sensitivity of the recommended Fluorescent Spot Test (FST) remains an issue as it misses out on the diagnosis of some deficient female heterozygotes and G6PD-deficient individuals undergoing acute hemolysis

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