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Q 2: Is dual-action therapy more effective than GLP-1 alone
But Novartis doesnt want to just be a me-too. Gal likens the situation with GLP-1s to whats happening in China, where a burst of innovation has led to concerns about the real gains being made there and whether many drugs are simply offering incremental improvements over existing options, particularly in oncology
More importantly, GLP-1 receptor agonists also show potential in promoting neurogenesis
Moreover, there is a need for additional studies that identify patients or sub-types of patients with various addictions who might benefit from treatment with such medications: for instance, the possibility that polymorphisms in the GLP-1R genes influence the treatment outcome of GLP-1R agonists on alcohol drinking in patients with AUD
A hard cutoff on eating 3 hours before bed dramatically reduces nighttime reflux
Magovern adds
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