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[2] In clinical trials (STEP programme), patients lost an average of 10-15% of their body weight over the treatment period, though individual responses vary considerably
Avoiding alcohol and limiting salt can further reduce stress on the kidneys
In clinical trials, Wegovy was shown to reduce body weight in people with body mass indexes, or BMIs, of 27 or greater by around 15% over 68 weeks
Acute brain slice preparation Experiments were performed on 6 to 8-week-old POMC-EGFP transgenic mice
However, the oral GLP-1 product, Rybelsus, has low bioavailability and requires cumbersome daily administration, which reduces its convenience
2E, F, H)
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