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Given the lack of individual preclinical models of PCOS that recapitulate all the metabolic, endocrine, and gonadal traits of the clinical syndrome, pharmacological testing was conducted in parallel in these two PCOS models, which are among the most reliable to mimic the metabolic and gonadal phenotype of women with PCOS 36,37 , capturing also the heterogeneity of this condition 38

47:21: Taubes claims the Pima Indians support his model because the babies are malnourished while the mothers are fat and makes an emotional appeal of how could a mother become fat while the baby is malnourished? As Joe and Stephan pointed out, disease plays a major role here, but Garys story relies on the adults telling the researchers that they were eating very little food

Some individuals have an immune response to these proteins, leading to inflammation and gut dysbiosis

10.1016/j.tox.2006.06.008 38

Resources: Pickart, L., & Margolina, A

Exenatide once weekly versus insulin glargine for type 2 diabetes (DURATION-3): 3-year results of an open-label randomised trial