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Coverage depends on the independent BCBS company, the member's exact plan and benefit year, employer choices, the prescribed product and FDA-labeled indication, and any prior-approval rules

In contrast, under oxidative stress NRF2 dissociates from KEAP1 and translocates to the nucleus, where it activates the downstream expression of antioxidative response element (ARE)-containing target genes, many of which have been shown to play a role in defending against ferroptosis [65, 66]

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Therefore, compared to other GLP-1R agonists, exendin-phe1 possesses advantageous pharmacological properties that maximizes insulin secretion

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