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Dasatinib+Quercetin, ABT-263, and other senolytic compound classes Structural biology FOXO4-DRI/p53TAD2 complex characterisation, disordered protein binding, and rational analogue design What Do Studies Say About FOXO4-DRI
says Dr
More Phase 3 readouts are expected in 2026 (again, that's based on public reporting around the trial programme)
Lee J, Pellegrini MV
Before that, though, he said they were going to take all the feedback they'd gotten from the meeting, go back to the drawing board and maybe have another meeting
It was designed to treat obesity by targeting peripheral receptors, but some researchers believe it might actually exert its effects through CB1 receptors in the central nervous system 15
