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A recent study set out to compare the effectiveness of focal shockwaves (f-ESWT) and radial shockwaves (r-ESWT) on knee osteoarthritis

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Based on the current evidence, this process can be conceptually divided into four interconnected phases: damage sensing, HSF activation and nuclear translocation, HSF transcription and translation with subsequent molecular chaperone activity, and finally repair or cell death (Kmiecik and Mayer, 2022