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However, we did observe higher increases in serum calcitonin levels, a tumor marker for medullary thyroid carcinoma, with increased doses of tirzepatide compared to placebo
These predispositions may influence appetite suppression sensitivity and metabolic response to tirzepatide, though genetics represents only one factor among many
The models have been used to predict pharmacokinetics in special populations, including those with hepatic or renal impairment, as well as in disease states such as type 2 diabetes and obesity
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