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It is important to note that while the potential risk of developing MEN is a concern, semaglutide has been shown to be an effective treatment for type 2 diabetes in many people
N., Kravchenko, M
GLP-1 medications: Increase insulin secretion Decrease glucagon release Slow gastric emptying Reduce appetite and hunger signaling Act on receptors in the central nervous system GLP-1 receptor activity in the brain, pancreas, liver, stomach, and adipose tissue, reinforce that these medications affect more than weight alone
Many participants receiving higher doses reached normalized liver fat levels , with large relative reductions on imaging and parallel improvements in insulin sensitivity and liver-related biomarkers