Your care team and dispensing pharmacy provide instructions on how to use your prescribed form safely
Some redness or mild sensitivity for a day or so is normal, and most people return to their regular routine the same day or the next
Drug Interaction Note: If you're taking nitrate-class cardiovascular medications, discuss potential interactions with any GLP-1 or metabolic medication with your prescribing provider and pharmacist before starting
In a later interview with People , published in December 2025, Winfrey revealed that just six months after starting GLP-1s, shed decided to see if she could beat the medication by stopping taking them
In Phase 2 clinical trials, patients showed progressive, dose-dependent weight loss of up to 24.2% of body weight with a 12 mg weekly dose
Headaches, nausea, kidney stones, asthma attacks in individuals with asthma, abdominal pain, chest tightness, and even kidney failure have also been reported as possible side effects