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During a congressional hearing last year, Senator Bernie Sanders repeatedly asked Novo Nordisk's chief executive officer Lars Frugaard Jrgensen why Americans pay more, demanding the company "Stop ripping us off!" In response, the firm blamed the complexities and "middlemen" of the American healthcare system
Furthermore, receptor overexpression in insulinomas and neuroendocrine tumors provides a basis for GLP-1R-targeted diagnostics and therapeutics [60, 61]
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Many of these conditions have resulted in hospitalization and even death
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Understanding this distinction helps explain why many commonly used pain medications particularly corticosteroids can provide short-term symptom relief while quietly worsening long-term metabolic, immune, and tissue health
