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Conflict of interest: The authors have declared that no conflict of interest exists

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When we take any food, medicine or even supplements by mouth the stomach dissolves them and then they must circulate or pass through the liver which detoxifies the substance this is called in medical terms the first-pass effect

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Ipamorelin is notable because, unlike earlier GHRPs, it produces GH release without significantly elevating cortisol or prolactin

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