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It was developed as a research compound under the code NNC 26-0161 and taken into a discontinued clinical study, so despite reaching human trials Ipamorelin holds no marketing authorisation in any jurisdiction

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Patients should be advised of the potential risk of dehydration in relation to gastrointestinal side effects and take precautions to avoid fluid depletion

Take-Home Messages The routine practice of stopping GLP-1 receptor agonists before surgery has shifted to individualised risk assessment