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It is worth noting, however, that the authors reported that pioglitazone was superior to SUs in providing cardiovascular protection to those who were either free from evident cardiovascular disease or were in the early stages of diabetes [52]

As genetic variants are determined at conception they are much less affected by the confounders that can bias conventional observational studies, such as socioeconomic position, so MR studies minimize confounding

(Abstract P3-450) 86th Annual Meeting of the Endocrine Society

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Using tirzepatide alongside growth hormone secretagogues like ipamorelin or CJC-1295 may preserve lean mass better during aggressive fat loss