Since semaglutide already impairs the normal B12 absorption pathway, using a form that requires fewer metabolic steps to become active reduces the total burden on an already stressed system
However, both medications do not target glucagon (GCG) receptor (GCGR)
It plays a major role in the development and progression of many chronic conditions, including heart disease, kidney disease, sleep apnea, and diabetes, all of which can worsen blood pressure control, she says
This means people following restricted diets may be more likely to develop low levels over time
It is also a cofactor for sirtuin proteins, which are involved in many metabolic activities and associated with longevity
Her arm became less swollen and softer, getting "significantly better after the weight loss, Dayan says