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The peptides were not FDA-approved
)
Individual responses to low doses also vary widely
A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself
If these medications stimulated human C-cells the way they stimulate rodent C-cells, calcitonin levels should rise during treatment
others require injection
Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, et al
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