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Researchers looked at data from 39 clinical trials with a total of 70,499 participants

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Numerous gut- and brain-derived peptides exert potent anorectic or orexigenic effects, often with effect sizes comparable to or exceeding those of GLP-1 in preclinical models

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9,120,131,132 A BISAP score 3 correlates strongly with adverse outcomes such as organ failure, persistent organ failure, and pancreatic necrosis

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