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[4] Finally, food itself can play a part

Portions may become easier to control

Both pathways, cAMP PKA and GHS-R1a, converge on the pituitary gland

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While more research is needed, the evidence so far suggests that GLP-1 medications may do more than just regulate metabolismthey could actively protect the brain from aging-related decline

After the FDA declared GLP-1 shortages resolved in early 2025 and began cracking down on compounding pharmacies, Ro and Hims & Hers shifted to partnering with Eli Lilly and Novo Nordisk's direct-to-consumer cash-pay pharmacies, LillyDirect (launched January 2024) and NovoCare (launched March 2025), that the manufacturers had built to bypass insurance and PBM channels and capture the unprecedented consumer demand around by GLP-1s, for which ~60% of patients are denied coverage by their insurers