Indomethacin inhibition of glutathione S-transferases [PMID: 6847692] Laboratory literature summary: Indomethacin inhibition of glutathione S-transferases
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a RWD: real-world data from cohort or registry studies (electronic health records, insurance-claims databases), b SRS: adverse drug reaction evidence from case reports and spontaneous-reporting systems, such as the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) and World Health Organization (WHO) VigiBase
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Given the risk of hemolytic crisis and related sequelae from various triggers in affected subjects in both malaria endemic and non-endemic regions, we believe that developing a pharmacological agent that corrects G6PD deficiency may benefit affected individuals