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ROS can damage DNA, proteins, and lipids and activate a variety of inflammatory pathways, all of which contribute to psoriatic inflammation [4, 5]

Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation

Also, biochemical evidence has indicated that the TKTL1 protein does not catalyze a transketolase reaction

Repeating treatment should depend on a defined goal, response, risk, cost, and clinician reassessment

References: Krinsky DL, LaValle JB, Hawkins EB, et al