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Variants such as X(SS2)a, X(SS2)c, X(SS2)f and X(SS2)g exhibited moderate activity on PC_SS2 while retaining activity on VAMP1 and PC_SS1, with no detected activity on procaspase-1 in the luminescence assay (Fig

A: Most evidence is from animal studies

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It should be avoided during breastfeeding due to a lack of research on its safety for infants