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WS-917 binds ABCB1, stimulates its ATPase activity, and reverses resistance by increasing intracellular paclitaxel by 730-fold, with low toxicity and synergy with CD8 + T-cell responses

from 95 to 10% phase B at 3.003.01 min, followed by re-equilibration at 10% phase B until 4 min and the flow rate was 0.5 ml/min

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