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For instance, exenatide, the first GLP-1-analogue developed, demonstrated to promote human monocyte differentiation into alternatively activated M2 macrophages, leading to an increase in anti-inflammatory cytokines such as IL-10 while significantly reducing pro-inflammatory cytokines, including IL-6, TNF- and IL-1 ( Furthermore, GLP-1 has been hypothesised to act as a mediator between innate and adaptive immune responses

"[The data] can influence policy and do things like ensure there is increased public awareness, increased testing it forms the basis of the science that is known about these risks," he said

However, supplementation should always be part of a broader, comprehensive management strategy that includes aggressive pacing, nervous system regulation, and targeted medical care