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The lack of ATP collapses the vesicular proton gradient, forcing stored catecholamines to leak out of the vesicles and flood the axoplasm/cytoplasm of the nerve terminal (Silver et al., 2001)
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Our medical programs are designed for efficiency, often involving weekly treatments and clear guidance that fits seamlessly into a hectic lifestyle, removing the guesswork
Key considerations in co-occurring eating disorders and substance use include: High rates of overlap between eating disorders and substance use disorders Increased medical, nutritional, and psychological risk when conditions interact Greater vulnerability to relapse if only one condition is addressed Effective care treats both conditions simultaneously rather than in isolation
Important safety considerations include a boxed warning for medullary thyroid carcinoma risk (contraindicated in patients with personal/family history of MTC or Multiple Endocrine Neoplasia syndrome type 2), and warnings regarding pancreatitis, gallbladder disease, and hypoglycemia risk when used with insulin or sulfonylureas
Just how large the addressable market for GLP-1s actually is, and what that means for the drug companies developing them, other exposed industries, and the wider economy, is Top of Mind
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