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Neurological symptoms like weakness, trembling, and difficulty in coordinating movements can also be indicative of a deficiency
Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning
Biochemistry 2009
Storage matters because peptides are fragile
The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation
The peptide storage guide provides general principles
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