The skin-lightening effects of glutathione vary from person to person, depending on the frequency of the treatments and the patients general health
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The samples were centrifuged, and the supernatant was subjected to a GSH assay based on a kinetic enzymatic recycling method that detects the oxidation of GSH by 5,5-dithiobis-2-nitrobenzoic acid (DTNB) and glutathione reductase to measure the GSH content in cells 74
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They hadnt been officially approved for use as drugs, however, and many had never been studied in humans