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In excess, free radicals cause oxidative stress, which can cause damage to cells and proteins if not properly balanced

A higher level of oxidative stress as evidenced by elevated plasma malondialdehyde levels and low levels of GSH, -tocotrienol and GSH peroxidase activity in patients under 45 years old may play a role in the development of premature coronary artery disease and be potential biomarkers for premature coronary artery disease (153)

While these findings are biologically plausible, they should be interpreted with caution and considered hypothesis-generating rather than confirmatory

L-carnitine investigation for congestive heart failureexperimental and laboratory study [PMID: 1538579] Laboratory literature summary: L-carnitine investigation for congestive heart failureexperimental and laboratory study

Researchers who have maintained high protein intake and consistent resistance training throughout the process lose primarily fat, while those who relied on appetite suppression alone show concerning ratios of muscle loss

Your healthcare team can discuss whether switching to an alternative agent or trying a different class of diabetes medication (such as SGLT2 inhibitors or DPP-4 inhibitors) might be appropriate for your individual circumstances, in line with NICE guidance