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Clinical utility in newborns Oxidative stress has a leading role in the spectrum of neonatal disease processes, and it has been known for more than 160 years that hyperoxia has toxic effects on different organs

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For instance, in NSCLC, treatment with first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) often leads to the development of the EGFR T790M mutation, while third-generation inhibitors subsequently select for the C797S mutation, both of which confer resistance

This hormone possesses both beneficial effects, including fighting the effects of aging, and also some potentially harmful ones, too

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