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High-Risk Demographic Targets: The vast majority of patients within the study who experienced active ischemic events fell into specific baseline sub-groups: predominantly men, or individuals between the ages of 50 and 65
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Thus, removal of the C-terminal L585 reduces the ability of the albumin fusions to engage human FcRn, and thereby compromises their rescue from intracellular lysosomal degradation
In case it goes out of date, dispose of it despite looking clear
