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Why 'Low and Slow' is the Standard Starting Point Doctors prescribe the lowest effective dose first for good reason

Glucose dependent insulin and glucagon secretion Semaglutide lowers high blood glucose concentrations by stimulating insulin secretion and lowering glucagon secretion in a glucose-dependent manner

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It has no FDA approval for any indication and carries significant side effects requiring careful management

This distinction is clinically significant because B12 deficiency-related neuropathy may be reversible with supplementation if detected early, whereas advanced diabetic neuropathy typically represents irreversible nerve damage

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