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Javor E et al
Patients should understand that discontinuing semaglutide often leads to significant weight regain unless substantial lifestyle changes have been implemented and even when a large percentage of patients still see weight regain after losing the initial weight with the help of semaglutide, explained Dr
Ghosal S, Datta D, Sinha B
Screening the child with DS for the MTHFR defect is helpful as well because the genetic polymorphism can be passed on to the child, compromising his or her health beyond existing issues from DS
By the end of the three months, participants receiving semaglutide lost approximately 9 to 9.5% of their baseline body weight, while those in the placebo group lost 6% of their body weight
Importantly, GLP-1RAs do not exert direct immunosuppressive effects but instead modulate inflammatory pathways indirectly through metabolic and cellular mechanisms, supporting a favourable safety profile when used alongside bDMARDs
