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Nausea, vomiting, diarrhea, and constipation are the most frequently reported side effects, typically appearing during the first few weeks of treatment as your body adjusts

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It has been demonstrated that blocking these sodium channels significantly attenuates or completely abolishes pain responses

Possible side effects include injection-site irritation, mild flushing, and occasional water retention during early cycles

Documentation must align with the place-of-service code reported and reflect clinical necessity for performing arthrocentesis in that setting

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