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Int J Endocrinol Metab 17(2):e84353
In the canonical pathway, NF-B-dependent transcription of inflammasome components and their assembly is triggered by alterations in intracellular homeostasis
Specifically, 63% of patients receiving semaglutide achieved resolution of steatohepatitis with no worsening of fibrosis, compared with 34% of those on placebo
These findings support the notion that differential redox capacity exists in different B cell subsets, and suggest that steady-state MZB require greater redox buffering capacity
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