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"If they regain weight later, their body composition worsens," he adds, noting that this "yo-yo cycle" of losing and regaining "raises the long-term risk of weight gain," especially when cycling on and off the medication
Shab-Bidar, S
The evolving framework under ICH S1B(R1) further emphasizes a modern, evidence-integrated approach to long-term safety evaluation
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Missed dose: Missed dose should be administered as soon as possible within 4 days
Inositol: Inositol, a naturally occurring compound belonging to the B-vitamin complex, plays a pivotal role in various physiological processes
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