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374 PU-H71 similarly reduces tau pathology and improves cognitive function in AD models

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Recommendations : 1 capsule daily with food

reported that AEG-1-C75S leads to dysregulation of specific differential gene expression in the hepatic periportal, mid-lobular, and pericentral regions, impairs hepatic metabolic homeostasis, and promotes MASH progression (161)

Net-beneficial preferred terms uric acid lowered -0.69/-0.92/-0.95 mg/dL (72.7% mediated by weight loss): Sattar Annals of the Rheumatic Diseases 2026