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Gut microbial disorders Ethanol and acetaldehyde can impair the intestinal mucosa and alter gut microbiota composition, facilitating the translocation of pathogen-associated molecular patterns (PAMPs), such as LPS, peptidoglycan, and lipoproteins, from the gut to the liver [34]

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Lipohypertrophy is a buildup of thickened, scar-like fatty tissue caused by repeated injections in the same location

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Constipation (8%), nausea (7%), and stomach pain (7%), among individuals receiving eluxadoline, were the most frequent side effects (61)

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