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Clinicians recommend not continuing GLP-1 medication while severe dehydration or other acute medical issues are being treated, and advise follow-up before restarting therapy
Mike Reinold: Thats what they always say
Participants receiving semaglutide demonstrated lower post-treatment drinking and craving scores, and while changes in overall drinking days were not observed, there was a progressive decline in heavy drinking days within the semaglutide group (Hendershot et al., 2025)
Self-monitoring at home should include: Weight tracking : Weekly weigh-ins at the same time of day, recorded in a diary or app, help identify trends whilst avoiding obsessive daily fluctuations Blood glucose monitoring : Patients with diabetes should test as advised by their healthcare team, typically including fasting and pre-meal readings, with increased frequency during dose adjustments Symptom diary : Recording side effects, appetite changes, and general wellbeing helps identify patterns and informs clinical discussions Dietary and activity logs : Tracking food intake and physical activity provides context for weight and glucose changes Clinical monitoring typically follows this schedule: 46 weeks : Initial review to assess tolerability, side effects, and early response
Its once-daily dosing, compared to Ozempic and Wegovys once-weekly dosing, provides flexibility in titration for prescribers and increased adherence for patients who may not be able to keep track of what day of the week they inject
