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Patients on tirzepatide (Zepbound) have seen upward of 20% total body weight loss, whereas semaglutide (Wegovy) averages around 15%
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28 Fluid loss due to EDKA can range from 6 L to 9 L, and rehydration is necessary for adequate tissue perfusion and resolution of metabolic abnormalities
Scenario 5: Denied, patient switched to compounded semaglutide out of pocket
Tirzepatide , the active ingredient in both Mounjaro and Zepbound is currently being evaluated in phase 3 trials for cardiovascular outcomes in diabetes patients, heart failure with preserved ejection fraction, morbidity and mortality in obesity, and obstructive sleep apnea (OSA)
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