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Metformin ameliorates polycystic ovary syndrome in a rat model by decreasing excessive autophagy in ovarian granulosa cells via the pi3k/akt/mtor pathway

The interplay between resveratrols pro-oxidant and antioxidant properties within co-formulations necessitates careful modulation to avoid paradoxical effects

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1) Trastuzumab emtansine Trastuzumab emtansine (T-DM1) is an anti-HER2 ADC composed of trastuzumab and the cytotoxic microtubule agent emtansine (DM1) linked via a non-cleavable linker, a maytansine derivative [22]