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Following Matrigel polymerization for 10 min at 37 C, advanced DMEM/F12 was supplemented with penicillin/streptomycin, 2 mM GlutaMAX, 10 mM HEPES, 1 B27, 1 N2 (Life Technologies), 1mM N-acetylcysteine (Sigma), and 10 nM gastrin I (Biogems)

TGF-beta pathway activation organizes the actin cytoskeleton in fibroblasts, restoring collagen contraction and remodeling capacity

Reduces Pigmentation: Glutathione helps reduce skin pigmentation by regulating the activity of the enzyme tyrosinase, which plays a key role in melanin production

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